Fig. 3

Cellular uptake of [⁶⁴Cu]CuCl₂ in spheroids derived from glioblastoma and astrocyte cell lines. Cellular uptake was measured at 1, 2, and 3 h after incubation with 0.09 MBq of [⁶⁴Cu]CuCl₂. Uptake values were normalized to the spheroids' mean area of each cell line and the maximum uptake measured at 1 h in U87 spheroids. Data are presented as mean values ± S.E.M. of 3 to 5 independent assays. *p < 0.05, **p < 0.01