Fig. 3

Shows the in vivo response of xenografts of both cell lines on cisplatin and vehicle (control). In total 6 mice were injected on both flanks with 2 × 10⁶ VU-SCC-1131 (A) cells per site and randomized to either cisplatin or control group, all tumors grew out sufficiently for further analysis. For VU-SCC-OE (B) 10 mice were injected with cells on both flanks and randomized to either a cisplatin or control group. Mice were treated intra-peritoneal with cisplatin 0.5 mg/kg or the control-vehicle (solvent) at days 0 and 7