Scheme 2From: Synthesis and preclinical evaluation of [11C]EAI045 as a PET tracer for imaging tumors expressing mutated epidermal growth factor receptorPetasis approach for the synthesis of [11C]EAI045 precursor, (i) methanol, room temperature, 22 h, 29%; (ii) dichloromethane, room temperature, 2.5 h, 56%; (iii) dichloromethane, room temperature, 19 h, 0%Back to article page