Scheme 1From: Synthesis and preclinical evaluation of [11C]EAI045 as a PET tracer for imaging tumors expressing mutated epidermal growth factor receptorIodination of EAI045, followed by the tritiodehalogenation: (i) N-iodosuccinimide, trifluoroacetic acid, dichloromethane, room temperature, 2.5 h; (ii) tritium gas, palladium on calcium carbonate, ethanol, room temperature, 4 hBack to article page