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Table 5 The predictive performance of I-PET/CT parameters in predicting disease progression

From: Evaluation of therapeutic effect and prognostic value of 18F-FDG PET/CT in different treatment nodes of DLBCL patients

 

Sensitivity

Specificity

PPV

NPV

Accuracy

VA

71.7

69.1

56.9

81.6

70.1

ΔSUVmax(LLR)1

84.8

74.1

65.0

89.6

78.0

ΔSUVmax(LLR)1 + VA

67.4

84.1

70.5

81.9

78.0

ΔTMTV1

43.5

91.4

74.1

74.0

74.0

ΔTMTV1 + VA

41.3

97.5

90.5

74.5

77.2

ΔTLG1

60.9

84.0

68.3

79.1

75.6

ΔTLG1 + VA

58.7

92.6

81.8

79.8

80.3

  1. PPV Positive Predictive Value, NPV Negative Predictive Value, VA Visual analysis, SUVmax maximum standardized uptake value, LLR lesion-to-liver ratio calculated as SUVmax of the residual divided by SUVmax of the liver, TMTV total metabolic tumor volume, TLG total lesion glycolysis, 1 interim compared to baseline