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EJNMMI Research

Table 1 Basic characteristics of clinical data of newly diagnosed DLBCL patients and their correlation with PET/CT metabolic parameters

From: Evaluation of therapeutic effect and prognostic value of 18F-FDG PET/CT in different treatment nodes of DLBCL patients

Characteristic

Total population

N = 127

SUVmax

(median)

p value

TMTV

(median)

p value

TLG

(median)

p value

No

%

Age (years)

  

0.184

 

0.802

 

0.944

 ≤ 60

46

36.2

26.77

–

363.87

–

2738.12

–

 > 60

81

63.8

29.98

–

188.51

–

1631.10

–

Gender

62

48.8

 

0.350

 

0.481

 

0.309

 Female

65

51.2

30.70

–

269.87

–

1961.89

–

 Male

62

48.8

28.18

–

206.27

–

1760.97

–

Stages

   

0.343

 

0.000***

 

0.000***

 I-II

45

35.4

39.04

–

84.50

–

709.31

–

 III-IV

82

64.6

29.69

–

419.06

–

3273.09

–

COO subtypes

   

0.805

 

0.834

 

0.844

 GCB

33

28.9

29.04

–

337.50

–

3268.23

–

 Non-GCB

81

71.7

29.87

–

193.68

–

1631.10

–

IPI score

   

0.950

 

0.000***

 

0.000***

 0–2

56

44.1

29.63

–

102.41

–

832.09

–

 3–5

71

55.9

29.07

–

420.60

–

3277.96

–

LDH

   

0.164

 

0.000***

 

0.000***

 Normal

54

42.5

27.70

–

84.50

–

604.14

–

 Elevated

73

57.5

30.48

–

419.56

–

3734.96

–

β2-MG

   

0.145

 

0.000***

 

0.000***

 Normal

54

42.5

26.12

–

110.09

–

947.81

–

 Elevated

73

57.5

30.64

–

420.60

–

3277.96

–

Ferritin

   

0.547

 

0.013*

 

0.014*

 Normal

77

60.6

29.42

–

151.18

–

1460.10

–

 Elevated

50

39.4

29.26

–

387.29

–

2741.69

–

  1. ***p < 0.001, **p < 0.01, *p < 0.05
  2. DLBCL diffuse large B cell lymphoma, PET/CT positron emission tomography/computed tomography, COO cell of origin, GCB germinal center B cell, IPI international prognostic index, LDH lactate dehydrogenase, β2-MG β2-microglobulin, SUVmax maximum standardized uptake value, TMTV total metabolic tumor volume, TLG total lesion glycolysis
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