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EJNMMI Research
Fig. 2 | EJNMMI Research

Fig. 2

From: Repeatability of [15O]H2O PET imaging for lower extremity skeletal muscle perfusion: a test–retest study

Fig. 2

Schematic representation of image-derived input functions (IDIFs) used for the three field of views: heart, lower legs and feet. To the left A, C and E, maximum intensity projections (MIP) of the peak activity to illustrate the arterial signal in the three field of views. To the right, the input functions for the heart (B, H-IDIF), lower leg (D, LL-IDIF) and feet (F, F-IDIF) field of views. The IDIF from the heart field of view (H-IDIF, A and B) was used to derive IDIFs for all field of views. Delay and dispersion from the heart to each lower leg were estimated from the arterial signal in the corresponding lower leg (C) and added to the H-IDIF to yield two LL-IDIFs (left and right, D). Similarly, delay from the lower leg to the feet was estimated from the arterial signal in each foot (E) (additional dispersion from lower leg to foot was ignored) and added to the LL-IDIFs to yield two F-IDIFs (left and right, F). The H-IDIF is shown in dotted lines in D and F for reference

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