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Table 4 ROC curves results of meta-ROI in identification for AD, aMCI and NC

From: Comparison of 18F-FDG PET and arterial spin labeling MRI in evaluating Alzheimer’s disease and amnestic mild cognitive impairment using integrated PET/MR

 

AUC

Sensitivity(%)

Specificity(%)

SUVR

rCBF

SUVR + rCBF

SUVR

rCBF

SUVR + rCBF

SUVR

rCBF

SUVR + rCBF

NC vs. aMCI

0.728

0.610

0.744

72.34

78.72

72.34

64.44

44.44

75.56

NC vs. AD

0.963

0.869

0.963

95.74

87.23

95.74

93.30

82.22

95.56

aMCI vs. AD

0.901

0.824

0.897

84.44

77.78

86.67

84.44

75.56

80.00

  1. SUVR was calculated from 18F-FDG PET images. AUC, area under ROC curve. SUVR, standard uptake value ratio. rCBF, relative cerebral blood flow. SUVR + rCBF, standard uptake value ratio combines with relative cerebral blood flow