Fig. 3
Blocking study results of 18F-ASEM PET/MRI and autoradiography. A, B 18F-ASEM PET/MRI showed no abnormally increased uptake in the denervated left tibialis anterior muscle (cross) relative to the control. The denervated muscle SUVmax was 0.68 and the control muscle SUVmax was 0.69. The denervated muscle SUVmax of.18F-ASEM PET/MRI was not significantly different from the control SUVmax (0.84 ± 0.10 vs. 0.72 ± 0.02, n = 5, P = 0.0796). C, D Autoradiography also demonstrated no significantly increased uptake in the denervated muscle relative to the control (95% confidence interval 0.83–1.22, n = 5)