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Fig. 1 | EJNMMI Research

Fig. 1

From: 18F-ASEM PET/MRI targeting alpha7-nicotinic acetylcholine receptor can reveal skeletal muscle denervation

Fig. 1

Denervation 1 week results of dynamic and static 18F-ASEM PET/MRI. A Dynamic 18F-ASEM PET/MRI showed increased uptake in the denervated left tibialis anterior muscle (red arrow) than in the control muscle (blue arrow). B Dynamic 18F-ASEM uptake by the denervated muscle slowly decreased after radiotracer injection. C Static 18F-ASEM PET/MRI also showed increased uptake in the denervated muscle (cross) than in the control muscle. The denervated muscle SUVmax was 1.33 and the control muscle SUVmax was 0.88. D The denervated muscle SUVmax of18F-ASEM PET/MRI was significantly higher than that of the control muscle (1.08 ± 0.31 vs. 0.66 ± 0.25, n = 11, P = 0.0033*)

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