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EJNMMI Research

Table 4 CE values indicating spatial overlap of MTVs on EARL1 and EARL2

From: Quantitative and clinical implications of the EARL2 versus EARL1 [18F]FDG PET-CT performance standards in head and neck squamous cell carcinoma

Segmentation method

Median CE

False-negative volume (cm3)

False-positive volume (cm3)

Adaptive threshold

0.15 (0.12–0.18)

0.98 (0.51–1.60)

0.39 (0.27–0.63)

SUV2.5

0.10 (0.09–0.14)

1.05 (0.31–1.60)

0.55 (0.41–0.81)

SUV3.5

0.13 (0.08–0.17)

0.56 (0.14–1.00)

0.45 (0.35–0.68)

SUV4.5

0.14 (0.09–0.23)

0.26 (0.11–0.60)

0.58 (0.40–0.74)

SUR2.5

0.14 (0.10–0.20)

0.46 (0.18–1.10)

0.34 (0.19–0.47)

SUR3.5

0.18 (0.11–0.25)

0.27 (0.06–0.62)

0.42 (0.20–0.50)

SUR4.5

0.23 (0.13–0.38)

0.21 (0.03–0.43)

0.34 (0.21–0.59)

MAX40%

0.16 (0.12–0.20)

0.69 (0.48–1.20)

0.26 (0.10–0.39)

MAX50%

0.17 (0.13–0.21)

0.45 (0.24–0.66)

0.22 (0.07–0.47)

  1. Values in parentheses represent the interquartile range. The false-negative volume is defined as MTV that is delineated on EARL1 but not on EARL2, and vice versa for the false-positive volume
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