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Table 3 Clinical variables of benign and malignant VCFs in the training and test groups

From: Value of 18F-FDG-PET/CT radiomics combined with clinical variables in the differential diagnosis of malignant and benign vertebral compression fractures

Clinical variable

Training (n = 100)

Test (n = 44)

Benign (n = 47)

Malignant (n = 53)

p Value*

Benign (n = 20)

Malignant (n = 24)

P Value

SULpeak

2.79 ± 0.90

5.72 ± 2.73

 < 0.001

2.73 ± 1.02

5.46 ± 3.08

 < 0.001

SULmax

3.45 ± 1.12

7.35 ± 3.59

 < 0.001

3.36 ± 1.15

7.16 ± 4.05

 < 0.001

SUVpeak

3.58 ± 1.08

7.37 ± 3.50

 < 0.001

3.43 ± 1.27

6.92 ± 3.90

 < 0.001

SUVmax

4.43 ± 1.35

9.46 ± 4.51

 < 0.001

4.23 ± 1.45

9.08 ± 5.08

 < 0.001

Age, year

71.68 ± 9.29

59.89 ± 14.40

 < 0.001

69.00 ± 8.74

62.25 ± 11.76

0.04

Osteolytic destruction

  

 < 0.001

  

0.003

 No

39 (82.98)

14 (26.42)

 

18 (90.00)

10 (41.67)

 

 Yes

8 (17.02)

39 (73.58)

 

2 (10.00)

14 (58.33)

 

Fracture line

  

 < 0.001

  

0.025

 No

29 (61.70)

51 (96.23)

 

13 (65.00)

23 (95.83)

 

 Yes

18 (38.30)

2 (3.77)

 

7 (35.00)

1 (4.17)

 

Soft tissue mass/swelling

  

0.097

  

0.974

 No

35 (74.47)

30 (56.60)

 

16 (80.00)

18 (75.00)

 

 Yes

12 (25.53)

23 (43.40)

 

4 (20.00)

6 (25.00)

 

Appendices/posterior vertebrae involvement

  

 < 0.001

  

0.034

 No

38 (80.85)

15 (28.30)

 

17 (85.00)

12 (50.00)

 

 Yes

9 (9.15)

38 (71.70)

 

3 (15.00)

12 (50.00)

 
  1. SUVmax maximum standardized uptake value; SUVpeak peak of standardized uptake value; SULmax maximum lean body mass correction of SUV; SULpeak peak of lean body mass correction of SUV
  2. *The differences were assessed by Mann–Whitney U test or student T-test
  3. Mean ± SD: mean ± standard deviation
  4. Percentage