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Table 3 Tumour-to-background ratios including contrast-to-noise ratios from HD/UHD-PET

From: Threshold for defining PSMA-positivity prior to 177Lu-PSMA therapy: a comparison of [68Ga]Ga-PSMA-11 and [18F]F-DCFPyL in metastatic prostate cancer

Lesion no

SUVmaxT/

SUVmeanL

SUVmeanT/

SUVmeanL

SUVmaxT/

SUVmeanM

SUVmeanT/

SUVmeanM

CNR

 

68Ga

18F

68Ga

18F

68Ga

18F

68Ga

18F

68Ga

18F

1

0.80

0.57

0.54

0.38

2.24

1.66

1.51

1.09

9.28

7.83

2

1.18

0.84

0.59

0.53

3.31

2.42

1.65

1.52

7.91

6.67

3

3.13

1.63

1.91

1.02

13.17

10.00

8.04

6.26

26.71

30.52

4

2.49

1.65

1.45

1.03

9.84

7.00

5.71

4.36

31.00

52.06

5

1.55

1.13

0.94

0.74

6.14

4.80

3.71

3.15

18.95

27.90

6

8.81

9.43

4.76

5.01

27.59

26.13

14.90

13.88

28.78

71.96

7

8.96

11.38

5.83

7.00

28.04

31.55

18.24

19.40

111.18

151.50

8

6.74

8.51

4.02

5.28

21.09

23.61

12.59

14.63

75.73

113.11

9

2.69

3.18

1.67

2.10

8.41

8.81

5.22

5.82

29.55

42.11

10

2.89

3.87

1.82

2.45

9.06

10.72

5.69

6.78

32.45

49.83

11

4.57

5.84

2.68

3.45

14.32

16.19

8.38

9.57

45.00

54.17

12

1.61

2.09

1.01

1.28

5.03

5.80

3.17

3.56

16.64

23.89

13

4.70

3.80

3.07

2.46

11.11

13.28

7.26

8.61

26.24

35.16

14

1.19

1.01

0.72

0.56

3.37

4.39

2.04

2.46

12.06

12.75

15

6.24

3.02

3.73

1.77

27.50

17.25

16.43

10.10

32.17

46.88

16

4.73

6.60

3.54

5.20

11.97

27.35

8.97

21.54

27.13

75.20

17

1.23

2.74

0.86

1.74

5.02

11.03

3.53

7.01

12.23

46.10

18

0.61

1.22

0.38

0.94

2.48

4.89

1.55

3.76

6.50

35.07

19

1.07

1.30

0.65

0.81

4.38

5.21

2.64

3.26

3.12

12.07

20

1.49

1.80

0.87

1.04

6.11

7.24

3.57

4.20

4.81

16.75

21

0.87

1.40

0.53

0.86

3.55

5.65

2.17

3.44

4.66

13.04

22

2.56

2.58

1.60

1.80

9.32

10.76

5.82

7.50

22.26

36.62

23

1.26

0.60

0.78

0.35

4.59

2.50

2.83

1.45

11.65

3.34

24

4.25

1.76

2.51

0.93

16.28

3.41

9.62

1.80

48.95

27.38

  1. SUV standardised uptake values corrected for body weight, HD high definition, UHD ultra-high definition, PET positron emission tomography, SUVmaxT/SUVmeanL Ratio of the maximum SUV in the tumour lesion to the mean SUV in the liver, SUVmeanT/SUVmeanL Ratio of the mean SUV in the tumour lesion to the mean SUV in the liver, SUVmaxT/SUVmeanM Ratio of the maximum SUV in the tumour lesion to the mean SUV in the mediastinum, SUVmeanT/SUVmeanM Ratio of the mean SUV in the tumour lesion to the mean SUV in the mediastinum, CNR contrast-to-noise ratio, 68Ga [68Ga]Ga-PSMA-11, 18F [18F]F-DCFPyL