Fig. 4
From: Automatic healthy liver segmentation for holmium-166 radioembolization dosimetry
Examples of automatic segmentation outcome. A–D. A 56-year-old male subject treated with 3850 MBq of 166Ho microspheres in the right liver. E–H. A 65-year-old male subject treated with 4982 MBq of 166Ho microspheres in the right liver. Panels A and E, and B and F, show the axial view of 166Ho and 99mTc SPECT/CT, respectively, while panels C and G show the coronal view of the LDCT acquired with the SPECT. Manual (solid green) and automatic (dashed magenta) segmentation is depicted. Upper panels (A–C, Sørensen–Dice coefficient = SDC = 0.62), show a clear discrepancy between segmentations, which is due to non-rigid deformation of liver because of breathing. Segmentations are quite comparable in the bottom panels (E–G, SDC = 0.84). Panels D and H show the resulting cumulative dose–volume histogram (DVH). Despite the segmentation differences, the corresponding dose difference is below 2 Gy