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EJNMMI Research

Table 3 Comparison of diagnostic accuracy for recurrence by tumor volume-corrected cutoff values

From: Optimization of diagnostic performance for differentiation of recurrence from radiation necrosis in patients with metastatic brain tumors using tumor volume-corrected 11C-methionine uptake

 

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Accuracy (%)

Non-corrected cutoff value (1.61)

70.6

80.8

83.7

61.8

74.0

MTV-corrected cutoff value

78.4

80.8

88.9

65.6

79.2

  1. PPV positive predictive value, NPV negative predictive value, MTV metabolic tumor volume, MTV-corrected optimal cutoff value MTV ≤ 0.5 cm3—cutoff 1.23, 0.5 < MTV ≤ 4 cm3—cutoff 1.54, MTV > 4 cm3—cutoff 1.85
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