Fig. 4From: Low kidney uptake of GLP-1R-targeting, beta cell-specific PET tracer, 18F-labeled [Nle14,Lys40]exendin-4 analog, shows promise for clinical imagingIn vivo retention and clearance of [18F]exendin-4 in rat. a Dynamic PET imaging revealed rapid tracer accumulation in the kidneys at early time points and, thereafter, rapid elimination. Uptake in lung and stomach wall was modest. b Coronal PET/CT image at 0–60 min p.i. c Tracer accumulation in the liver remained low. d Coronal PET/CT image at 360 min p.i. (N = 2–5 rats/scan)Back to article page