Table 2 Biodistribution data for [⁶⁸Ga]NOTA-pentixafor and [⁶⁸Ga]pentixafor in Daudi xenograft bearing CB-17 SCID mice (1.5 h p.i.) and relating tumor-to-organ ratios

Blood

0.65 ± 0.41

0.62 ± 0.26

0.97 ± 0.34

Heart

0.34 ± 0.19

0.36 ± 0.14

0.58 ± 0.17

Lung

0.73 ± 0.25

0.95 ± 0.38

1.32 ± 0.29

Liver

2.30 ± 0.88

2.02 ± 0.76

2.05 ± 0.27

Gallbladder

3.61 ± 3.00

5.14 ± 2.24

Pancreas

0.12 ± 0.05

0.16 ± 0.05

1.06 ± 0.22

Spleen

0.44 ± 0.22

0.54 ± 0.19

0.30 ± 0.10

Kidney

2.71 ± 1.06

3.56 ± 1.03

1.65 ± 0.91

Adrenals

0.52 ± 0.30

0.48 ± 0.15

3.68 ± 0.72

Stomach

0.45 ± 0.21

0.58 ± 0.24

0.48 ± 0.08

Intestine

1.89 ± 0.83

3.97 ± 0.92

0.67 ± 0.21

Muscle

0.13 ± 0.10

0.13 ± 0.05

0.19 ± 0.06

Bone

0.25 ± 0.18

0.16 ± 0.07

n/a

Tumor

1.71 ± 0.40

0.52 ± 0.17

16.2 ± 3.82

 T/blood

2.64 ± 1.78

16.7 ± 7.05

 T/liver

0.74 ± 0.34

7.90 ± 2.13

 T/kidney

0.63 ± 0.29

9.81 ± 5.89

 T/muscle

13.0 ± 9.86

85.2 ± 33.6