Table 2 Experimental design of the PET/CT and SPECT/CT imaging studies
From: Preclinical in vivo application of 152Tb-DOTANOC: a radiolanthanide for PET imaging
Mouse | Radiopeptide | Injected activity (IA) | Injected DOTANOC | Scan start (scan duration) | Radioactivity at scan start | Imaging method | Figure |
|---|---|---|---|---|---|---|---|
M1 | 152Tb-DOTANOC | ~3.4 MBq | 0.34 nmol | 2 h p.i. (20 min) | ~0.52 MBq | PET/CT | Fig. 4 |
M2 | 152Tb-DOTANOC | ~25 MBq | 2.5 nmol | 5 h p.i. (20 min) | ~1.87 MBq | PET/CT | Fig. 5a |
8 h p.i. (20 min) | ~1.46 MBq | PET/CT | Fig. 5b | ||||
22 h p.i. (20 min) | ~0.44 MBq | PET/CT | Fig. 5c | ||||
M3 | 152Tb-DOTANOC | ~47 MBq | 4.7 nmol | 22 h p.i. (30 min) | ~0.83 MBq | PET/CT | Fig. 6a |
32 h p.i. (30 min) | ~0.45 MBq | PET/CT | Additional file 1: Fig. S1a | ||||
M4 | 177Lu-DOTANOC | ~47 MBq | 4.7 nmol | 22 h p.i. (4 h)b | ~2.5 MBq | SPECT/CT | Fig. 6b |