EJNMMI Research

Table 1 Sequences of 13 peptides on beads bound to U-87MG cells from screening focused OBOC library 1 (cyclic cdGX₁GX₂X₃c and cdGX₁GX₂X₃cX₄)

From: Discovery and characterization of a high-affinity and high-specificity peptide ligand LXY30 for in vivo targeting of α3 integrin-expressing human tumors

No.	X₁	X₂	X₃	X₄
1	HoPhe	Hyp	Phe(4-Me)
2 (LXY21)	Phe(3,5-diF)	Hyp	Y
3 (LXY23)	Phe(3,5-diF)	Hyp	Orn	W
4	L	P	R
5	Phe(4-Me)	Hyp	N
6 (LXY8)	L	Hyp	N	D
7	Nle	Hyp	W	R
8 (LXY20)	L	Hyp	D-Thi
9 (LXY22)	L	Hyp	R
10 (LXY10)	L	Hyp	D	G
11 (LXY19)	Phe(3,5-diF)	Hyp	S
12 (LXY1)	L	Hyp	N
13	L	Hyp	S	R

Natural amino acids are designated by the standard single letter code
Other abbreviations: HoPhe homophenylalanine, Hyp hydroxyproline, Phe(4-Me) 4-methylphenylalanine, Phe(3,5-diF) 3,5-difluorophenylalanine, Orn ornithine, Nle norleucine, D-Thi D-3-(2-thienyl)alanine

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