EJNMMI Research

Table 1 Protein binding (n = 6) and stability (n = 3) values after 30, 60 and 120 min incubation at RT for ⁶⁸Ga- and ¹⁷⁷Lu-labelled compounds

From: Influence of a novel, versatile bifunctional chelator on theranostic properties of a minigastrin analogue

Incubation time [min]	A [%]		B [%]		C [%]		D [%]
Incubation time [min]	⁶⁸Ga	¹⁷⁷Lu	⁶⁸Ga	¹⁷⁷Lu	⁶⁸Ga	¹⁷⁷Lu	⁶⁸Ga	¹⁷⁷Lu
30	9.5 ± 0.4	4.9 ± 0.7	96 ± 2.1	99 ± 0.27	94 ± 1.6	92 ± 0.24	90 ± 3.2	97 ± 0.47
60	13.0 ± 1.2	4.9 ± 1.0	95 ± 2.7	98 ± 0.24	91 ± 1.6	87 ± 0.31	88 ± 2.1	98 ± 0.12
120	15.8 ± 1.8	3.7 ± 0.8	92 ± 5.5	98 ± 0.12	90 ± 0.5	77 ± 0.72	81 ± 7.9	97 ± 2.12

Data are shown as means ± SD
A serum protein binding; B stability in EDTA solution; C stability in DTPA solution; D stability in fresh human serum

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