Early side effects and first results of radioligand therapy with 177Lu-DKFZ-617 PSMA of castrate-resistant metastatic prostate cancer: a two-centre study

EJNMMI Research

Table 5 Nephrotoxicity

Number	Cr	CTC Cr	GFR (ml/min)	CTC GFR	Baseline TER MAG3	Second TER MAG3
1	1.0	1	>70	1	183	179
2	1.3	0	56	0	125	104
3	0.8	0	>70	0	245	209
4	0.6	0	>70	0	186	178
5	1.5	2	50	2	92	96
6	0.7	0	>70	0	208	220
7	0,6	0	>70	0	270	284
8	1,2	0	>70	0	156	220
9	0,8	0	>70	0	214	214
10	0,9	0	>70	0	231	256

Cr creatinine, GFR glomerular filtration rate, TER MAG3 tubular extraction rate of MAG3 (ml/min/1.73 m² BSA)

Number	Cr	CTC Cr	GFR (ml/min)	CTC GFR	Baseline TER MAG3	Second TER MAG3
1	1.0	1	>70	1	183	179
2	1.3	0	56	0	125	104
3	0.8	0	>70	0	245	209
4	0.6	0	>70	0	186	178
5	1.5	2	50	2	92	96
6	0.7	0	>70	0	208	220
7	0,6	0	>70	0	270	284
8	1,2	0	>70	0	156	220
9	0,8	0	>70	0	214	214
10	0,9	0	>70	0	231	256

Number	Cr	CTC Cr	GFR (ml/min)	CTC GFR	Baseline TER MAG3	Second TER MAG3
1	1.0	1	>70	1	183	179
2	1.3	0	56	0	125	104
3	0.8	0	>70	0	245	209
4	0.6	0	>70	0	186	178
5	1.5	2	50	2	92	96
6	0.7	0	>70	0	208	220
7	0,6	0	>70	0	270	284
8	1,2	0	>70	0	156	220
9	0,8	0	>70	0	214	214
10	0,9	0	>70	0	231	256

Number	Cr	CTC Cr	GFR (ml/min)	CTC GFR	Baseline TER MAG3	Second TER MAG3
1	1.0	1	>70	1	183	179
2	1.3	0	56	0	125	104
3	0.8	0	>70	0	245	209
4	0.6	0	>70	0	186	178
5	1.5	2	50	2	92	96
6	0.7	0	>70	0	208	220
7	0,6	0	>70	0	270	284
8	1,2	0	>70	0	156	220
9	0,8	0	>70	0	214	214
10	0,9	0	>70	0	231	256