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EJNMMI Research

Table 1 Biodistribution data (%ID/g) of [ 18 F]-7B in FVB mice ( n = 3)

From: Synthesis, characterization, and preclinical validation of a PET radiopharmaceutical for interrogating Aβ (β-amyloid) plaques in Alzheimer’s disease

Organ (%ID/g)

5.00 min

30.00 min

60.00 min

120.00 min

Blood

3.18 ± 0.23

2.51 ± 0.09

2.40 ± 0.17

1.86 ± 0.05

Brain

7.23 ± 0.47

2.27 ± 0.13

2.00 ± 0.15

1.55 ± 0.01

Bone

1.61 ± 0.20

2.08 ± 0.13

3.41 ± 0.37

5.27 ± 0.34

Liver

16.22 ± 1.43

5.21 ± 0.08

3.44 ± 0.20

2.73 ± 0.16

Kidney

6.72 ± 0.44

2.83 ± 0.09

2.20 ± 0.07

1.59 ± 0.03

  1. %ID, percentage injected dose.
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