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Table 2 Comparison of haemodynamic state of the brain at baseline and after 3 months between patients assigned to intervention and those to standard treatment ( n= 23)

From: Intervention versus standard medical treatment in patients with symptomatic occlusion of the internal carotid artery: a randomised oxygen-15 PET study

 

Intervention n = 12

Standard n = 11

Unadjusted difference in change (95% CI)

Adjusted difference in change *(95% CI)

  

Mean ± SD

Mean ± SD

  

CBF MCA (mL/min/100 mL)

Baseline

31.3 ± 5.9

33.1 ± 5.4

  

3 months

31.6 ± 4.9

33.5 ± 4.7

  

Change

0.34 ± 6.2

0.42 ± 4.1

−0.1 (−4.7 to 4.5)

−1.0 (−7.4 to 5.4)

CBF ACA (mL/min/100 mL)

Baseline

32.6 ± 5.8

35.2 ± 5.5

  

3 months

32.0 ± 4.2

35.0 ± 5.7

  

Change

−0.56 ± 6.2

−0.28 ± 4.9

−0.3 (−5.2 to 4.6)

−1.6 (−8.4 to 5.2)

CBV MCA (mL/100 mL)

Baseline

3.0 ± 0.6

3.3 ± 0.9

  

3 months

3.5 ± 1.4

3.2 ± 0.6

  

Change

0.60 ± 1.7

−0.09 ± 1.2

0.7 (−0.6 to 2.0)

0.09 (−1.7 to 1.9)

CBV ACA (mL/100 mL)

Baseline

3.0 ± 0.6

3.4 ± 1.0

  

3 months

3.5 ± 1.3

3.1 ± 0.7

  

Change

0.49 ± 1.6

−0.23 ± 1.3

0.7 (−0.6 to 2.0)

0.08 (−1.6 to 1.8)

OEF MCA (%)

Baseline

46.4 ± 9.7

47.5 ± 5.5

  

3 months

46.3 ± 7.9

48.4 ± 5.8

  

Change

−0.08 ± 6.1

0.85 ± 6.8

−0.9 (−6.5 to 4.7)

3.1 (−4.1 to 10.3)

OEF ACA (%)

Baseline

44.4 ± 11.2

46.1 ± 6.2

  

3 months

44.2 ± 7.3

47.2 ± 5.2

  
 

Change

−0.17 ± 7.4

1.1 ± 6.3

−1.3 (−7.3 to 4.7)

3.1 (−4.6 to 10.8)

  1. Asterisk ‘*’ indicates adjusted for age and sex; measurements were performed ipsilateral to the side of the ICA occlusion; CBF, cerebral blood flow; CBV, cerebral blood volume; OEF, oxygen extraction fraction; MCA, middle cerebral artery; ACA, anterior cerebral artery.