From: Cardioprotective effects of adenosine within the border and remote areas of myocardial infarction
Control (n = 7) | CADO (n = 8) | 8-SPT (n = 8) | |
---|---|---|---|
48 h | |||
Extent of MI area (% of LV) | 35 ± 6 | 32 ± 15 | 32 ± 21 |
EDV (μL) | 412 ± 61 | 397 ± 57 | 441 ± 66 |
ESV (μL) | 239 ± 48 | 230 ± 43 | 257 ± 74 |
EF (%) | 42 ± 7 | 42 ± 6 | 42 ± 7 |
1 month | |||
Extent of MI area (% of LV) | 32 ± 9 | 29 ± 14 | 33 ± 23 |
Change from 48 h | −3 ± 7 | −3 ± 4 | 1 ± 7 |
EDV (μL) | 600 ± 95 | 576 ± 111 | 666 ± 175 |
Change from 48 h | 188 ± 76 | 179 ± 120 | 225 ± 160 |
ESV (μL) | 353 ± 67 | 324 ± 106 | 428 ± 185 |
Change from 48 h | 114 ± 61 | 94 ± 112 | 171 ± 149 |
EF (%) | 42 ± 2 | 45 ± 9 | 38 ± 12 |
Change from 48 h | 0 ± 8 | 3 ± 10 | −5 ± 7 |
2 months | |||
Extent of MI area (% of LV) | 30 ± 11 | 26 ± 15 | 32 ± 27 |
Change from 48 h | −5 ± 9 | −7 ± 8 | 0 ± 9 |
EDV (μL) | 692 ± 132 | 637 ± 151 | 780 ± 232 |
Change from 48 h | 280 ± 113 | 241 ± 158 | 339 ± 212 |
ESV (μL) | 432 ± 120 | 379 ± 149 | 530 ± 210 |
Change from 48 h | 19 ± 99 | 149 ± 145 | 273 ± 174 |
EF (%) | 38 ± 5 | 42 ± 8 | 34 ± 10 |
Change from 48 h | −4 ± 6 | 0 ± 8 | −9 ± 6 |