Imaging of the appearance time of cerebral blood using [15O]H2O PET for the computation of correct CBF

EJNMMI Research

Table 1 Means and SDs of ATB and CBF obtained using the four methods for groups 0, 1, and 2

	Parietal	Frontal	Temporal	Occipital	Deep gray matter	Cerebellum
Group 0
ATB (s)	−0.6 ± 1.6	−0.3 ± 1.3	−0.4 ± 1.4	0.1 ± 1.7	−0.8 ± 1.7	1.9 ± 1.3^a
CBF (ml/min/g)
BFMAT	0.36 ± 0.06	0.38 ± 0.09	0.42 ± 0.09	0.45 ± 0.12	0.41 ± 0.12	0.45 ± 0.11
ARG	0.35 ± 0.06	0.37 ± 0.07	0.41 ± 0.08	0.45 ± 0.09	0.40 ± 0.10	0.46 ± 0.09
BFMF	0.37 ± 0.06	0.39 ± 0.08	0.42 ± 0.08	0.46 ± 0.09	0.42 ± 0.11	0.44 ± 0.09
BFMP	0.37 ± 0.06	0.39 ± 0.08	0.42 ± 0.10	0.46 ± 0.09	0.42 ± 0.10	0.48 ± 0.09
Group 1
ATB (s)	−1.1 ± 1.7	−0.1 ± 1.9	−1.1 ± 1.8	0.6 ± 1.7	−0.5 ± 1.8	2.2 ± 2.0^a
CBF (ml/min/g)
BFMAT	0.33 ± 0.09	0.36 ± 0.13	0.39 ± 0.13	0.43 ± 0.07	0.43 ± 0.09	0.46 ± 0.16
ARG	0.32 ± 0.08	0.36 ± 0.11	0.38 ± 0.12	0.43 ± 0.07	0.42 ± 0.09	0.45 ± 0.12
BFMF	0.33 ± 0.09	0.36 ± 0.11	0.39 ± 0.10	0.43 ± 0.06	0.44 ± 0.08	0.43 ± 0.10
BFMP	0.33 ± 0.09	0.37 ± 0.11	0.38 ± 0.12	0.43 ± 0.07	0.44 ± 0.09	0.47 ± 0.13
Group 2
ATB (s)	−0.8 ± 1.0	0.3 ± 1.4	−0.5 ± 1.0	−0.2 ± 1.5	−0.4 ± 1.7	1.6 ± 1.7^a
CBF (ml/min/g)
BFMAT	0.32 ± 0.07	0.34 ± 0.10	0.36 ± 0.11	0.38 ± 0.10	0.38 ± 0.11	0.39 ± 0.14
ARG	0.31 ± 0.07	0.34 ± 0.10	0.36 ± 0.11	0.38 ± 0.09	0.37 ± 0.10	0.40 ± 0.10
BFMF	0.33 ± 0.07	0.34 ± 0.09	0.37 ± 0.10	0.38 ± 0.10	0.38 ± 0.10	0.38 ± 0.08
BFMP	0.33 ± 0.07	0.35 ± 0.10	0.37 ± 0.11	0.39 ± 0.09	0.38 ± 0.10	0.43 ± 0.11

ATB, appearance time of blood (negative number corresponds to earlier appearance); CBF, cerebral blood flow. ^aSignificantly different.