Figure 1From: Preclinical evaluation of carbon-11 and fluorine-18 sulfonamide derivatives for in vivo radiolabeling of erythrocytes Synthesis of [18 F]-(3) and [11 C]-(4). Reagents and conditions: (i) AEBS, dichloromethane, pyridine for 72 h at room temperature, (ii) CH3ONa, HCL 1 M, and (iii) (a) DMF, 1-bromo-2-fluoroethane, 70°C, 16 h; (b) DMF, Cs2CO3, 11CH3I, 90°C, 15 min; (c) DMF, Cs2CO3, 18FEtBr, 90°C, 15 min.Back to article page