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Table 2 Global ( R )-[ 11 C]verapamil BP ND in healthy controls and Alzheimer's disease patients after dichotomization on presence of T

From: Blood–brain barrier P-glycoprotein function in healthy subjects and Alzheimer's disease patients: effect of polymorphisms in the ABCB1 gene

 

Number

HC

Number

AD

C1236

no T

11

1.76 ± 0.45

3

1.74 ± 0.33

 

T present

21

1.78 ± 0.43

14

2.16 ± 0.29*

G2677T/A

no T

11

1.76 ± 0.45

3

1.74 ± 0.33

 

T present

21

1.78 ± 0.43

14

2.16 ± 0.29*

C3435T

no T

8

1.73 ± 0.49

2

1.56 ± 0.15

 

T present

24

1.79 ± 0.42

15

2.15 ± 0.28*

  1. HC, healthy control group; AD, Alzheimer's disease patient group; * = p < 0.05.