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EJNMMI Research

Table 3 Radiation-associated genes

From: Transcriptional response of BALB/c mouse thyroids following in vivo astatine-211 exposure reveals distinct gene expression profiles

Gene symbol

Log 2ratio values

0.05 Gy

0.5 Gy

1.4 Gy

11 Gy

32 Gy

Amy1 (Mycbp)

−4.6

−4.8

−3.6

−3.0

−4.5

Amy2

−5.8

−5.7

−4.8

−4.4

−5.6

Apaf1

     

Bag-1

     

Batf3

     

Bax

     

Ccnb1

     

Ccnd1

 

0.6

−0.9

  

Ccne1

     

Ccng1

     

Cdc25

     

Cdkn1a

 

−0.6

   

Dd2

     

Ddb2

     

Ephx2

 

−0.8

   

Fen1

     

Fhl2

     

Flt3

     

Fos

  

1.1

  

Gadd45a

  

0.8

  

Gadd45g

0.6

 

1.1

  

Gja1

 

−1.2

   

Gjb2

0.7

0.9

−0.9

0.8

 

Hiap

     

Hrad23b

     

Iap3

     

Icsbp1

     

Jun

     

Xrcc6 (Ku70)

−0.7

−0.9

   

Mak10

     

Makp8pi

     

Mapk1

     

Mapk3

     

Mdm2

     

Noxa

     

Ogg1

     

Pcna

     

Plcg2

 

0.7

 

0.7

 

Rad51l1

     

Rhoa

     

Tgfb3

 

1.0

   

Tgfbr2

−0.7

−0.9

   

Tnfaip8

  

0.7

  

Tnfrsf10b

     

Tnfrsf19

0.7

0.6

 

0.7

 

Tnfrsf21

0.7

1.0

 

0.9

0.6

Tp53

     

Trp53inp1

0.7

 

0.8

0.9

0.7

Trp53inp2

 

−0.6

   

Ttf

     

Wee

     

Vegfb

 

−0.8

   

Xab2

     

X-iap

     

Xpc

     

Xrcc1

     
  1. Genes associated with radiation-induced biological response according to Snyder and Morgan [13] and Chaudhry [14]. Values for gene expression are given as comparison log2 ratio values. Note that the Illumina MouseRef-8 Beadchip is a whole-genome expression assay; however, some gaps in the genome do exist, and several genes are represented under other aliases.
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