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Table 2 Total number of regulated transcripts in 131I irradiated tissues

From: Effects of internal low-dose irradiation from 131I on gene expression in normal tissues in Balb/c mice

  

Number of transcripts regulated per injected activity

 

Total number of transcripts regulated

13 kBq 131 I

130 kBq 131 I

260 kBq 131 I

Kidney medulla

423

160

↑50 (31%)

158

↑65 (41%)

208

↑65 (31%)

   

↓110 (69%)

 

↓93 (59%)

 

↓143 (69%)

Kidney cortex

260

154

↑87 (56%)

85

↑30 (35%)

93

↑60 (65%)

   

↓67 (44%)

 

↓55 (65%)

 

↓33 (35%)

Liver

738

417

↑250 (60%)

427

↑264 (62%)

455

↑292 (64%)

   

↓167(40%)

 

↓163(38%)

 

↓163(36%)

Lung

857

320

↑149(47%)

113

↑82(73%)

596

↑475(80%)

   

↓171(53%)

 

↓31(27%)

 

↓121(20%)

Spleen

607

240

↑158(66%)

306

↑240(78%)

238

↑176(74%)

   

↓82(34%)

 

↓66(22%)

 

↓62(26%)

  1. Data on changes in gene expression after i.v. injection of 13, 130, or 260 kBq. The total number of transcripts regulated in the tissues investigated is given together with the number of up- (arrows pointing up) and downregulated (arrows pointing down) transcripts given as the total number and percentage (in parentheses).