EJNMMI Research

Table 1 Growth inhibition for tumor volume of 500 and 1,000 mm³ after treatment

From: Experimental α-particle radioimmunotherapy of breast cancer using ²²⁷Th-labeled p-benzyl-DOTA-trastuzumab

Treatment	Dosage	500 mm ³		1,000 mm ³
		Days ^a	Growth delay ^b	Days	Growth delay
NaCl		15 ± 7	0 ± 10	25 ± 7	0 ± 11
Trastuzumab (pooled)	20 - 250 μg	15 ± 7	0 ± 11	23 ± 8	-2 ± 12
²²⁷Th-rituximab	400 and 600 kBq/kg	15 ± 8	-3 ± 11	27 ± 10	2 ± 11
²²⁷Th-trastuzumab	200 kBq/kg	22 ± 8	7 ± 11	32 ± 8	7 ± 12
²²⁷Th-trastuzumab	400 kBq/kg	38 ± 8	23 ± 10	70 ± 10	45 ± 12
²²⁷Th-trastuzumab	600 kBq/kg	60 ± 7	45 ± 7	90 ± 10	65 ± 7

^aThe number of days to reach the chosen tumor volume. ^bGrowth delay = days (treatment) - days (NaCl).

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