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EJNMMI Research
Fig. 2 | EJNMMI Research

Fig. 2

From: [99mTc]-labelled anti-Programmed Death-Ligand 1 single-domain antibody SPECT/CT: a novel imaging biomarker for myocardial PD-L1 expression

Fig. 2

Baseline [99mTc]NM-01 SPECT/CT images for a patient with non-small cell lung cancer. In addition to the uptake of [99mTc]-labelled anti-PD-L1 single-domain antibody (NM-01) in the right lung tumour, tracer uptake is seen in the myocardium. The left ventricular: blood pool maximum region of interest (ROImax) ratio was 3.1, and the right ventricular: blood pool ratio was 1.5. In addition, there is a normal distribution of hepatic, bone marrow, splenic and renal activity. Very low muscle activity is present in the paraspinal muscles, in contrast to the increased myocardial PD-L1 expression

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