CMR validation of left ventricular volumes and ejection fraction measured by the IQ-SPECT system in patients with small heart size

EJNMMI Research

Table 4 Comparison of cardiac function parameters obtained by IQ-SPECT and CMR using different reconstruction parameters

	Normal heart size	Small heart size	Normal heart size vs. CMR	Small heart size vs. CMR
3–10
EDV	87.7 ± 14.9	46.2 ± 9.9	< 0.001*	< 0.001*
ESV	43.8 ± 10.0	14.7 ± 6.5	< 0.001*	< 0.001*
LVEF	50.6 ± 4.3	69.5 ± 8.6	0.117^#	0.009*
5–12
EDV	88.1 ± 14.8	49.4 ± 9.8	< 0.001*	< 0.001*
ESV	44.5 ± 10.2	19.2 ± 6.9	< 0.001*	< 0.001*
LVEF	50.0 ± 4.3	62.1 ± 7.8	0.051^#	0.120^#
5–15
EDV	88.4 ± 14.9	51.1 ± 9.6	< 0.001*	< 0.001*
ESV	45.6 ± 10.4	20.9 ± 7.0	< 0.001*	< 0.001*
LVEF	49.0 ± 4.2	60.0 ± 7.1	0.013*	0.005*
8–12
EDV	89.5 ± 15.2	52.3 ± 9.8	< 0.001*	< 0.001*
ESV	47.4 ± 10.4	22.6 ± 7.2	0.001*	0.004*
LVEF	47.4 ± 3.9	57.7 ± 7.3	< 0.001*	< 0.001*
8–15
EDV	89.7 ± 14.8	53.1 ± 9.3	< 0.001*	< 0.001*
ESV	49.3 ± 10.6	24.1 ± 7.1	< 0.001*	0.025*
LVEF	45.7 ± 5.0	55.3 ± 6.9	< 0.001*	< 0.001*
8–18
EDV	90.9 ± 14.4	53.8 ± 9.9	< 0.001*	< 0.001*
ESV	50.2 ± 10.7	24.8 ± 7.3	0.001*	0.054^#
LVEF	45.1 ± 4.3	54.6 ± 6.9	< 0.001*	< 0.001*
CMR
EDV	129.7 ± 21.5	78.2 ± 18.8
ESV	60.7 ± 11.7	28.0 ± 10.6
LVEF	53.2 ± 5.8	64.6 ± 8.8

^*Represents P < 0.05; # represents P > 0.05, indicating a statistically nonsignificant difference
EDV end-diastolic volume, ESV end-systolic volume, LVEF left ventricular ejection fraction, CMR cardiovascular magnetic resonance