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Table 1 Baseline characteristics of patients

From: 18F-FDG-PET/CT-based deep learning model for fully automated prediction of pathological grading for pancreatic ductal adenocarcinoma before surgery

Variable

Low grade (n = 190)

High grade (n = 180)

p value

Demographics

   

Age (years), mean ± SD

59.90 ± 9.22

60.28 ± 9.52

0.698

Gender

  

0.066

 Female

93 (49%)

71 (39%)

 

 Male

97 (51%)

109 (61%)

 

BMIa

23.4 (21.47–25.9)

23.44 (22.03–25.13)

0.449

Smoke

59 (31%)

60 (33%)

0.639

Drink alcohol

45 (24%)

60 (33%)

0.04

Abdominal discomfort

88 (46%)

99 (55%)

0.095

Weight loss(> 5 kg)

39 (21%)

57 (30%)

0.015

PET/CT parameters

   

Tumor size (mm)a

   

 Max

31.5 (26.0–45.0)

31 (27.0–42.0)

0.728

 Min

26 (20.0–35.5)

25 (19.5–33.0)

0.254

Tumor SUVmaxa

5.75 (4.4–7.95)

7.5 (5.6–9.6)

0.001

Liver SUVmean

2.30 (2.02–2.54)

2.30 (2.02–2.54)

0.974

SUVR

2.74 (1.60–3.01)

3.48 (2.27–4.11)

0.003

Location

  

0.01

 Head–neck

103 (54%)

121 (67%)

 

 Body–tail

87 (46%)

59 (33%)

 

Pathological report

   

Neuroaggression

113 (59%)

109 (61%)

0.832

Cancer embolus

15 (8%)

38 (21%)

0.001

Lymph node metastasis

58 (31%)

58 (32%)

0.834

Laboratory findingsa

   

ALT(U/L)

22.2 (11.5–58.7)

17.2 (13.2–98.5)

0.159

AST(U/L)

17.70 (13.5–49.3)

18.75 (13.5–50.8)

0.369

Total bilirubin(umol/L)

12.4 (8.7–18.6)

15.7 (8.7–32.7)

0.007

Direct bilirubin(umol/L)

4.4 (2.9–8.8)

4.9 (2.7–20.5)

0.037

Glucose (mmol/L)

5.97 (5.2–7.0)

5.48 (4.8–6.9)

0.162

CEA (μg/L)

2.77 (1.8–5.0)

3.02 (2.0–4.7)

0.325

CA125(U/mL)

14.46 (8.7–25.4)

18.96 (11.7–34.7)

0.004

CA199(U/mL)

170.25 (47.8–611.2)

229 (70.5–738.4)

0.027

  1. aData in parentheses are the interquartile range
  2. BMI, Body Mass Index; ALT, alanine aminotransferase; AST, aspartate amino transferase; CEA, Carcinoma Embryonic Antigen; CA 125, carbohydrate antigen 125; CA 199, carbohydrate antigen 199