Table 1 Participants’ characteristics by global visual read result
Total | VR− | VR+ | p | |
|---|---|---|---|---|
(n = 352) | (n = 295, 83.8%) | (n = 57, 16.2%) | ||
Age, y | 61.1 (4.7) | 60.5 (4.5) | 63.9 (4.2) | < 0.001* |
Education, y | 13.4 (3.5) | 13.5 (3.5) | 12.9 (3.8) | 0.21 |
Females | 216 (61.4) | 182 (61.7) | 34 (59.6) | 0.77 |
APOE-ε4 carriers | 193 (54.8) | 152 (51.5) | 41 (71.9) | 0.01* |
Annualized cognitive change | ||||
PACC | 0.01 (0.12) | 0.01 (0.11) | − 0.01 (0.13) | 0.12 |
Total paired recall | 0.20 (0.91) | 0.23 (0.90) | 0.02 (0.94) | 0.08 |
Visual puzzles | − 0.04 (0.94) | − 0.04 (0.95) | − 0.06 (0.89) | 0.72 |
Matrix reasoning | − 0.04 (1.09) | − 0.04 (1.05) | − 0.03 (1.30) | 0.94 |
Digit span forward | − 0.03 (0.31) | − 0.02 (0.29) | − 0.03 (0.38) | 0.95 |
Digit span backward | − 0.01 (0.31) | 0.00 (0.33) | − 0.01 (0.29) | 0.99 |
Digit span sequencing | − 0.01 (0.37) | 0.01 (0.35) | − 0.06 (0.46) | 0.34 |
Coding | − 0.17 (2.23) | − 0.05 (2.26) | − 0.75 (1.99) | 0.07 |
Centiloids | 4.47 (18.34) | 4.67 (18.63) | 3.30 (17.04) | 0.917 |
Total hippocampal volume, mm3 | 7500 (700.9) | 7512 (693.9) | 7437 (739.9) | 0.54 |
Total intracranial volume, cm3 | 1445.8 (175.7) | 1447.1 (170.1) | 1439.2 (203.9) | 0.76 |