Table 2 Ex vivo metabolite analysis in blood of [18F]EW-7197 and [11C]LR111
From: Imaging the TGFβ type I receptor in pulmonary arterial hypertension
Compound | [18F]EW-7197 | [11C]LR111 | ||
|---|---|---|---|---|
Time p.i. (min) | 15 | 45 | 15 | 60 |
Intact tracer (%) | 55 ± 16 | 23 ± 5 | 74 ± 5 | 46 ± 2 |
Non-polar metabolites (%) | 17 ± 7 | 25 ± 5 | 21 ± 5 | 31 ± 0 |
Polar-metabolites (%) | 28 ± 9 | 52 ± 1 | 5 ± 1 | 23 ± 2 |