Table 1 Injected doses of [18F]EW-7197, [11C]LR111, SB431542, cyclosporine and animal weights of each experimental group
From: Imaging the TGFβ type I receptor in pulmonary arterial hypertension
Control group (n = 4) | MCT group (n = 6) | SuHx group (n = 6) | ||||||
|---|---|---|---|---|---|---|---|---|
Day 1 | Day 2 | Day 3 | Day 4 | Day 1 | Day 2 | Day 1 | Day 2 | |
Animal weight (g) | 289 ± 2 | 253 ± 20 | 301 ± 22 | |||||
[11C]LR111 (MBq) | 12 ± 7 | 23 ± 0 | 16 ± 3 | 14 ± 5 | 17 ± 3 | 22 ± 4 | 22 ± 2 | 18 ± 1 |
[18F]EW-7197 (MBq) | 14 ± 2 | 17 ± 5 | 13 ± 1 | 14 ± 1 | 15 ± 2 | 19 ± 4 | 18 ± 8 | 19 ± 1 |
SB431542 (mg kg−1) | 20 | 20 | 20 | 20 | ||||
Cyclosporine A (mg kg−1) | 50 | 50 | ||||||