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EJNMMI Research
Fig. 3 | EJNMMI Research

Fig. 3

From: The added values of 18F-FDG PET/CT in differentiating cancer recurrence and osteoradionecrosis of mandible in patients with treated oral squamous cell carcinoma

Fig. 3

PET/CT image A obtained from a patient with left buccal cancer (T3N2bM0; AJCC stage IVA) diagnosed at 59 years of age. The patient had an elevated mandibular TLG (149.28 g, see main text), but the voxel site of SUVmax (asterisk) was located with bone predominance (CT HU: 340.0). A score of 1 was assigned. The results of histopathology revealed the presence of mandibular osteoradionecrosis (ORN). PET/CT image B obtained from a patient with left buccal cancer (T3N1M0; AJCC stage III) diagnosed at 56 years of age. The patient had an elevated mandibular TLG (73.66 g) and showed a voxel site of SUVmax located with soft tissue predominance (asterisk) (CT HU: 186.0). A score of 2 was assigned. The results of histopathology revealed the presence of mandibular cancer recurrence. PET/CT image C obtained from a patient with left buccal cancer (T3N2bM0; AJCC stage IVA) diagnosed at 67 years of age. The patient had a low mandibular TLG (51.27 g) and showed a voxel site of SUVmax located with soft tissue predominance (asterisk) (CT HU: 97.2). A score of 1 was assigned. The results of histopathology revealed the presence of mandibular ORN. PET/CT image D obtained from a patient with a score of 3. He was diagnosed with left lower gum cancer (T2N0M0, stage II) at 45 years of age. The patient had an elevated mandibular TLG (175.47 g) and showed a voxel site of SUVmax located with soft tissue predominance (asterisk) (CT HU: 18.0). The results of histopathology revealed the presence of mandibular cancer recurrence

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