[18F] FDG uptake in patients with spondyloarthritis: correlation with serum inflammatory biomarker levels

EJNMMI Research

Table 3 Correlation between PET indices and serum inflammatory biomarker levels in untreated axSpA and pSpA patients

	PET indices (n = 7)	CRP (n = 7)		ESR (n = 5)		MMP-3 (n = 5)
	PET indices (n = 7)	ρ	P	ρ	P	ρ	P
Untreated axSpA	MaxSUVmax	0.468	0.289	0.600	0.285	0.300	0.624
	Number of positive regions	− 0.027	0.954	0.300	0.624	− 0.308	0.614
	Total score	0.180	0.699	0.600	0.285	− 0.200	0.747

	PET indices (n = 17)	CRP (n = 17)		ESR (n = 10)		MMP-3 (n = 13)
	PET indices (n = 17)	ρ	P	ρ	P	ρ	P
Untreated pSpA	MaxSUVmax	0.792	< 0.001	0.527	0.117	0.467	0.108
	Number of positive regions	0.798	< 0.001	0.529	0.116	0.669	0.012
	Total score	0.808	< 0.001	0.515	0.128	0.703	0.007

axSpA Axial spondyloarthritis; pSpA Peripheral spondyloarthritis; SUVmax Maximum standardized uptake value; CRP C-reactive protein; ESR Erythrocyte sedimentation rate; MMP-3 Matrix metalloproteinase 3