[18F] FDG uptake in patients with spondyloarthritis: correlation with serum inflammatory biomarker levels

EJNMMI Research

Table 2 Correlation between PET indices and serum inflammatory biomarker levels in untreated and treated SpA patients

	PET indices (n = 24)	CRP (n = 24)		ESR (n = 15)		MMP-3 (n = 18)
	PET indices (n = 24)	ρ	P	ρ	P	ρ	P
Untreated SpA	MaxSUVmax	0.771	< 0.001	0.527	0.043	0.449	0.062
	Number of positive regions	0.644	< 0.001	0.514	0.050	0.499	0.035
	Total score	0.684	< 0.001	0.534	0.040	0.551	0.018

	PET indices (n = 12)	CRP (n = 12)		ESR (n = 6)		MMP-3 (n = 8)
	PET indices (n = 12)	ρ	P	ρ	P	ρ	P
Treated SpA	MaxSUVmax	0.434	0.159	0.429	0.397	− 0.143	0.736
	Number of positive regions	0.326	0.301	0.493	0.321	0.156	0.713
	Total score	0.396	0.203	0.429	0.397	0.071	0.867

SpA Spondyloarthritis; SUVmax Maximum standardized uptake value; CRP C-reactive protein; ESR Erythrocyte sedimentation rate; MMP-3 Matrix metalloproteinase 3