Skip to main content

Table 2 Parameters of 68Ga-DOTATATE and 18F-FDG dual tracer PET/MR based on tumor grade

From: The potential application of MR-derived ADCmin values from 68Ga-DOTATATE and 18F-FDG dual tracer PET/MR as replacements for FDG PET in assessment of grade and stage of pancreatic neuroendocrine tumors

Parameters

G1

G2

G3-NEC*

P (G1v G2)

P (G2 v NEC)

P (G1 v NEC)

FSUVmax

2.5 (2.1–7.3)

5.0 (2.8–9.3)

11.5 (8.1–13.6)

0.04

0.15

0.05

MTV

2.3 (1.1–6.1)

7.1 (2.5–28.4)

68 (51.6–804.3)

0.04

0.03

 < 0.01

TLG

3.8 (1.8–19)

24.8 (4.6–129.4)

505.7 (396.1–3168.3)

0.03

0.03

 < 0.01

GSUVmax

60.6 (37.8–99.5)

41.9 (19.0–72.4)

18.5 (4.5–23.4)

0.11

0.10

0.02

SRD

5.6 (3.1–20.6)

12.1 (6.7–44.8)

55.5 (27.5–705.9)

0.11

0.08

0.02

TLSRD

121.8 (60.3–427.2)

197.3 (52.8–1392.2)

236 (118.7–2597.1)

0.68

0.61

0.32

ADCmin

885.1 ± 140.4

703.4 ± 85.2

277.5 ± 79.2

 < 0.01

 < 0.01

 < 0.01

ADCmean

1485.2 ± 234.4

1322.0 ± 301.9

811.9 ± 79.4

0.04

 < 0.01

 < 0.01

  1. Values are presented as median with interquartile range (IQR) in parentheses. The statistically significant differences are highlighted in bold
  2. SUV Standardized uptake value, MTV Metabolic tumor volume, TLG Total lesion glycolysis, SRD Somatostatin receptor density, TLSRD Total lesion somatostatin receptor density
  3. *Numbers in parentheses are ranges