Impact of framing scheme optimization and smoking status on binding potential analysis in dynamic PET with [11C]ABP688

EJNMMI Research

Table 1 Summary of all tested cases and correspondent results for smoking effects on BP_ND

Framing scheme	Smoking status groups	F-test	P-value	η²p*
(a) Const 5 min	*A-1* 16 HC (8 S and 8 nS)	9.389	0.005	0.238
	16 SZ (8 S and 8 nS)	9.389	0.005	0.238
	*A-2* 15 HC (9 S and 6 nS)	28.323	< 0.001	0.503
	15 SZ (9 S and 6 nS)	28.323	< 0.001	0.503
	*A-3* 15 HC (9 S and 6 nS)	112.607	< 0.001	0.801
	15 SZ (9 S and 6 nS)	112.607	< 0.001	0.801
(b) Const Trues	*B-1* 16 HC (8 S and 8 nS)	86.450	< 0.001	0.742
	16 SZ (8 S and 8 nS)	86.450	< 0.001	0.742
	*B-2* 15 HC (9 S and 6 nS)	79.076	< 0.001	0.739
	15 SZ (9 S and 6 nS)	79.076	< 0.001	0.739
	*B-3* 15 HC (9 S and 6 nS)	68.590	< 0.001	0.710
	15 SZ (9 S and 6 nS)	68.590	< 0.001	0.710

^*Effect size
Table 1 Analysis for both framing schemes with balanced (cases A-1 and B-1) and unbalanced groups (cases A-2, A-3, B-2 and B-3) with regard to smoking statuses in the subgroups. The results for the effect of smoking on BP_ND were obtained with the general linear model