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Fig. 3 | EJNMMI Research

Fig. 3

From: Vessel-by-vessel analysis of lower extremity 18F-NaF PET/CT imaging quantifies diabetes- and chronic kidney disease-induced active microcalcification in patients with peripheral arterial disease

Fig. 3

Qualitative and quantitative analyses of lower extremity 18F-NaF PET/CT imaging in healthy control subjects and patients with PAD. Representative 18F-NaF PET/CT images of a A healthy control subject, B PAD patient without DM, and C PAD patient with DM, which reveal increasing arterial uptake of 18F-NaF and established calcium burden with worsening disease status. Quantitative vessel-by-vessel PET/CT image analysis demonstrates D DM- and E CKD-induced differences in arterial uptake of 18F-NaF between patient groups for each lower extremity artery of interest. White arrows denote regions of focal uptake of 18F-NaF in patients with PAD. Values represent means ± SEM

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