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EJNMMI Research

Table 1 Average estimates of VT and BPND from 19 healthy volunteers with measured AIFs for 120-min scan duration

From: Development of a minimally invasive simultaneous estimation method for quantifying translocator protein binding with [18F]FEPPA positron emission tomography

Brain region

HABs

MABs

VT (ml/cm3)

BPND

VT (ml/cm3)

BPND

Frontal

13.4 ± 2.1

5.8 ± 1.4

8.8 ± 1.3

2.9 ± 0.5

13.7 ± 3.2

8.5 ± 2.6

Temporal

14.9 ± 2.6

5.6 ± 1.4

8.7 ± 1.7

2.8 ± 0.6

14.3 ± 2.8

7.8 ± 2.4

Cerebellum

13.4 ± 1.8

5.4 ± 1.1

8.0 ± 1.9

2.4 ± 0.8

12.7 ± 2.9

7.6 ± 2.8

Thalamus

14.3 ± 1.9

5.8 ± 1.2

8.9 ± 1.3

2.7 ± 0.8

14.5 ± 3.8

8.8 ± 2.1

Insula

14.9 ± 2.5

5.7 ± 1.2

8.7 ± 0.34

3.1 ± 0.4

15.7 ± 4.6

9.0 ± 1.7

Caudate

13.1 ± 1.6

5.2 ± 1.3

9.0 ± 0.7

2.9 ± 0.6

12.68 ± 3.3

8.1 ± 1.2

  1. VT determined by SIME (top) and the 2TCM (bottom, italic), while BPND was only derived from SIME
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