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EJNMMI Research
Fig. 4 | EJNMMI Research

Fig. 4

From: Development of a minimally invasive simultaneous estimation method for quantifying translocator protein binding with [18F]FEPPA positron emission tomography

Fig. 4

a Blood-to-plasma ratios (BPRs) from arterial (red filled) and venous (blue filled) blood samples (results are from 8 animals). b Corresponding [18F]FEPPA plasma percent determined from venous (blue hollow) and arterial (red hollow) samples. Each value represents the mean ± standard deviation and are presented for 10 time points ranging from 2.5 to 180 min. c Linear correlation between venous and arterial BPRs (R2 = 0.93, slope = 0.94, intercept = 0.06). d Correlation between remaining [18F]FEPPA fraction from venous and arterial blood samples (R2 = 0.98, slope = 1.14, intercept = − 5.11). Note that figures c and d appear to show only nine points because of the overlap of two datasets (specifically at arterial BPR = 0.97, venous BPR = .85 and arterial fraction = 24, venous fraction = 23)

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