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EJNMMI Research
Fig. 2 | EJNMMI Research

Fig. 2

From: Correlation between molar activity, injection mass and uptake of the PARP targeting radiotracer [18F]olaparib in mouse models of glioma

Fig. 2

A Biodistribution in selected tissues in U251MG or U87MG xenograft-bearing mice, 120 min after i.v. injection of [18F]olaparib (0.28–0.31 MBq, molar activity = 1.9 GBq/μmol) (n = 3/group), with or without an excess of unlabelled olaparib (20 μg). Further data are presented in Additional file 1: Table S1 and Figure S2. B Autoradiography of U87MG tumour sections showing 18F localisation, and immunohistochemical staining of adjacent U87MG tumour sections showing PARP1, 2 and 3 expression. Asterisks indicate levels of significance: ***P < 0.001; ****P < 0.0001

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