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EJNMMI Research
Fig. 1 | EJNMMI Research

Fig. 1

From: Correlation between molar activity, injection mass and uptake of the PARP targeting radiotracer [18F]olaparib in mouse models of glioma

Fig. 1

A Western blotting for PARP1-3 expression in U251MG and U87MG lysates. B Chemical structure of [18F]olaparib, and its uptake in U251MG and U87MG cells ([TotalF]olaparib final concentration: 0.1 μM, molar activity = 11.8 GBq/μmol). C Blocking of [18F]olaparib uptake in U251MG and U87MG cells by unlabelled olaparib or talazoparib. D Mean fluorescence intensity (MFI) for PARP1-3 of U87MG cells treated with unlabelled olaparib (0–1 μM), assessed by flow cytometric analysis. n = 3 independent experiments. Representative histogram frequency is presented in Additional file 1: Fig. S1. Asterisks indicate levels of significance: *P < 0.05

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