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Table 1 Pharmacokinetic parameters of 131I-PD-L1-mAb

From: Radioimmunotherapy study of 131I-labeled Atezolizumab in preclinical models of colorectal cancer

Parameters

 

Cmax(%IA/g)

47.83 ± 22.38

Cl(ml/h)

0.22 ± 0.07

AUC0→∞(%IA/g*h)

733.09 ± 125.00

T1/2Z(h)

67.81 ± 21.54

MRT0→∞(h)

78.53 ± 21.79

  1. Cmax maximum concentration, Cl clearance rate, AUC area under curve, T1/2Z elimination half-life, MRT mean residence time