Table 4 Potential diagnostic indicators and results of the logistic regression for infection, malignancy, and NIID models
From: Diagnostic models for fever of unknown origin based on 18F-FDG PET/CT: a prospective study in China
Categories | Characteristics | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
OR (95% CI) | p value | OR (95% CI) | p value | ||
Infection | Low SUVmax of spleen, bone marrow, and lymph nodes | 4.21 (2.63–6.76) | < 0.01 | 2.18 (1.31–3.65) | 0.01 |
Low SUVmax of liver ratio | 2.19 (1.57–3.04) | < 0.01 | 2.52 (1.25–5.09) | < 0.01 | |
IGRA positive | 6.46 (3.20–13.05) | < 0.01 | 13.09 (4.83–35.44) | < 0.01 | |
ANA and ANCA negative | 13.27 (3.13–56.36) | < 0.01 | 20.23 (4.36–93.82) | < 0.01 | |
Low ESR | 3.88 (2.04–7.40) | < 0.01 | 8.04 (3.45–18.75) | < 0.01 | |
High platelet | 4.43 (2.10–9.37) | < 0.01 | 5.84 (2.10–16.23) | < 0.01 | |
Low neutrophilic percentage | 4.06 (2.33–7.08) | < 0.01 | 3.62 (1.77–7.38) | < 0.01 | |
Low LDH | 4.04 (2.61–6.27) | < 0.01 | 3.46 (1.83–6.53) | < 0.01 | |
Rash negative | 2.80 (1.59–4.93) | < 0.01 | 2.81 (1.30–6.07) | < 0.01 | |
Malignancy | SUVmax | 1.25 (1.18–1.32) | < 0.01 | 1.34 (1.24–1.46) | < 0.01 |
LDH /100 | 1.16 (1.09–1.22) | < 0.01 | 1.30 (1.16–1.46) | < 0.01 | |
Low SF | 1.58 (0.82–3.04) | 0.17 | 9.89 (2.87–34.09) | < 0.01 | |
High nasopharynx SUVmax | 8.37 (3.07–22.77) | < 0.01 | 6.59 (1.59–27.29) | < 0.01 | |
Weight loss | 4.00 (2.34–6.83) | < 0.01 | 6.19 (2.70–14.22) | < 0.01 | |
Low platelet | 6.10 (3.66–10.16) | < 0.01 | 5.96 (2.72–13.05) | < 0.01 | |
Splenomegaly | 6.12 (3.53–10.62) | < 0.01 | 3.91 (1.64–9.32) | < 0.01 | |
NIID | ANA or ANCA positive | 12.28 (5.53–27.29) | < 0.01 | 64.74 (18.74–223.65) | < 0.01 |
Low SUVmax of liver ratio | 6.55 (2.91–14.76) | < 0.01 | 15.32 (4.26–55.03) | < 0.01 | |
High platelet | 3.19 (1.85–5.47) | < 0.01 | 9.75 (3.65–26.03) | < 0.01 | |
Rash positive | 4.58 (2.63–7.97) | < 0.01 | 11.06 (4.33–28.28) | < 0.01 | |
High SF | 4.12 (2.36–7.18) | < 0.01 | 7.02 (2.69–18.27) | < 0.01 | |
High neutrophilic percentage | 4.43 (2.88–6.83) | < 0.01 | 6.69 (3.43–13.06) | < 0.01 | |
Young | 2.56 (1.53–4.29) | < 0.01 | 3.03 (1.34–6.86) | < 0.01 | |