Table 3 Cognitive test results stratified by test time and amyloid status
All | Amyloid positive | Amyloid negative | Group difference | |
|---|---|---|---|---|
MMSE baseline | 27.2 ± 1.8 (N = 34) | 26.8 ± 2.0 (N = 15) | 27.5 ± 1.6 (N = 19) | t(26) = – 1.13 |
MMSE follow-up | 26.0 ± 3.0 (N = 27) | 24.4 ± 2.7 (N = 11) | 27.2 ± 2.8 (N = 16) | t(22) = – 2.63* |
MMSE delta | – 1.3 ± 2.8* | – 2.8 ± 2.4** | – 0.2 ± 2.6 | t(23) = – 2.75* |
Logical memory I baseline | 8.7 ± 3.6 (N = 34) | 7.3 ± 3.3 (N = 15) | 9.8 ± 3.5 (N = 19) | t(31) = – 2.08* |
Logical memory I follow-up | 8.2 ± 4.0 (N = 26) | 5.9 ± 3.2 (N = 10) | 9.6 ± 3.9 (N = 16) | t(22) = – 2.60* |
Logical memory I delta | – 0.8 ± 3.0 | – 1.3 ± 2.3 | – 0.5 ± 3.4 | t(24) = – 0.72 |
Logical memory II baseline | 6.6 ± 3.9 (N = 34) | 5.5 ± 3.9 (N = 15) | 7.5 ± 3.7 (N = 19) | t(30) = – 1.57 |
Logical memory II follow-up | 6.1 ± 4.9 (N = 26) | 3.5 ± 4.6 (N = 10) | 7.8 ± 4.4 (N = 16) | t(18) = – 2.33* |
Logical memory II delta | – 0.6 ± 3.8 | – 1.6 ± 3.2 | 0.1 ± 4.1 | t(22) = – 1.15 |
Fluency baseline | 10.0 ± 5.3 (N = 34) | 9.9 ± 6.8 (N = 15) | 10.2 ± 3.8 (N = 19) | t(21) = – 0.15 |
Fluency follow-up | 8.5 ± 3.5 (N = 26) | 5.9 ± 2.3 (N = 10) | 10.1 ± 3.1 (N = 16) | t(23) = – 3.87*** |
Fluency delta | – 1.1 ± 4.1 | – 2.8 ± 5.0 | 0.0 ± 3.0 | t(13) = – 1.60 |