Table 2 PET imaging results stratified by test time and amyloid status

Composite score baseline

1.49 ± 0.36 (N = 34)

1.84 ± 0.24 (N = 15)

1.21 ± 0.06 (N = 19)

t(15) = 10.00***

Composite score follow-up

1.54 ± 0.39 (N = 25)

1.96 ± 0.24 (N = 10)

1.26 ± 0.12 (N = 15)

t(12) = 8.65***

Composite score delta

0.09 ± 0.10***

0.15 ± 0.10**

0.05 ± 0.08*

t(16) = 2.64*

Prefrontal cortex baseline

1.52 ± 0.39 (N = 34)

1.91 ± 0.25 (N = 15)

1.22 ± 0.06 (N = 19)

t(15) = 10.29***

Prefrontal cortex follow-up

1.57 ± 0.41 (N = 25)

2.01 ± 0.25 (N = 10)

1.27 ± 0.12 (N = 15)

t(12) = 8.84***

Prefrontal cortex delta

0.09 ± 0.11***

0.15 ± 0.12**

0.05 ± 0.08*

t(15) = 2.36*

Parietal cortex baseline

1.46 ± 0.35 (N = 34)

1.81 ± 0.24 (N = 15)

1.19 ± 0.08 (N = 19)

t(17) = 9.75***

Parietal cortex follow-up

1.53 ± 0.38 (N = 25)

1.93 ± 0.22 (N = 10)

1.26 ± 0.16 (N = 15)

t(15) = 8.15***

Parietal cortex delta

0.10 ± 0.10***

0.16 ± 0.08***

0.06 ± 0.10*

t(22) = 2.56*

Lateral temporal cortex baseline

1.46 ± 0.33 (N = 34)

1.78 ± 0.24 (N = 15)

1.20 ± 0.06 (N = 19)

t(15) = 9.01***

Lateral temporal cortex follow-up

1.51 ± 0.37 (N = 25)

1.91 ± 0.24 (N = 10)

1.24 ± 0.10 (N = 15)

t(11) = 8.38***

Lateral temporal cortex delta

0.08 ± 0.09***

0.14 ± 0.09***

0.04 ± 0.06*

t(15) = 3.04**

Anterior cingulate baseline

1.74 ± 0.43 (N = 34)

2.16 ± 0.29 (N = 15)

1.40 ± 0.09 (N = 19)

t(16) = 9.68***

Anterior cingulate follow-up

1.69 ± 0.44 (N = 25)

2.18 ± 0.26 (N = 10)

1.37 ± 0.11 (N = 15)

t(11) = 9.37***

Anterior cingulate delta

0.03 ± 0.13

0.09 ± 0.15

–0.01 ± 0.10

t(14) = 1.93

Posterior cingulate baseline

1.88 ± 0.46 (N = 34)

2.30 ± 0.38 (N = 15)

1.55 ± 0.12 (N = 19)

t(16) = 7.43***

Posterior cingulate follow-up

1.82 ± 0.42 (N = 25)

2.22 ± 0.39 (N = 10)

1.56 ± 0.14 (N = 15)

t(11) = 5.11***

Posterior cingulate delta

0.02 ± 0.12

0.03 ± 0.15

0.02 ± 0.10

t(14) = 0.24

Precuneus baseline

1.67 ± 0.49 (N = 34)

2.17 ± 0.30 (N = 15)

1.28 ± 0.07 (N = 19)

t(15) = 11.27***

Precuneus follow-up

1.68 ± 0.49 (N = 25)

2.23 ± 0.25 (N = 10)

1.32 ± 0.11 (N = 15)

t(11) = 10.89***

Precuneus delta

0.08 ± 0.10***

0.14 ± 0.12**

0.04 ± 0.06*

t(13) = 2.29*